marzo 2016 Nuova Pubblicazione su Support Care Cancer “Scrambler Therapy for the management of chronic pain”

Support Care Cancer DOI 10.1007/s00520-016-3177-3
Received: 8 December 2015 / Accepted: 11 March 2016 # Springer-Verlag Berlin Heidelberg 2016

Scrambler Therapy for the management of chronic pain

Neil Majithia - Thomas J. Smith – Patrick J. Coyne – Salahadin Abdi – Deirdre R. Pachman- Daniel Lachance –  Randy Shelerud – Andrea Cheville – Jeffrey R. Basford-  David Farley-  Carrie O’Neill – Kathryn J. Ruddy – Frank Sparadeo-  Andreas Beutler –  Charles L Loprinzi


Purpose Chronic pain is a widespread and debilitating condi- tion, encountered by physicians in a variety of practice set- tings. Although many pharmacologic and behavioral strate- gies exist for the management of this condition, treatment is often unsatisfactory. Scrambler Therapy is a novel, non- invasive pain modifying technique that utilizes trans- cutaneous electrical stimulation of pain fibers with the intent of re-organizing maladaptive signaling pathways. This review was conducted to further evaluate what is known regarding the mechanisms and mechanics of Scrambler Therapy and to investigate the preliminary data pertaining to the efficacy of this treatment modality.

Methods The PubMed/Medline, SCOPUS, EMBASE, and Google Scholar databases were searched for all articles pub- lished on Scrambler Therapy prior to November 2015. All case studies and clinical trials were evaluated and reported in a descriptive manner.

Results To date, 20 reports, of varying scientific quality, have been published regarding this device; all but one small study, published only as an abstract, provided results that appear positive.

Conclusion The positive findings from preliminary studies with Scrambler Therapy support that this device provides ben- efit for patients with refractory pain syndromes. Larger, ran- domized studies are required to further evaluate the efficacy of this approach.

Scarica la Pubblicazione : 1.13 Scrambler Therapy for the management of chronic pain 03-2016

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